Alcohol use disorder is a burden to society creating social and health problems. Detection of AUD and its effects on the brain are difficult to assess. This problem is enhanced by the comorbid use of other substances such as nicotine that has been present in previous studies. Recent machine learning algorithms have raised the attention of researchers as a useful tool in studying and detecting AUD. This work uses AUD and controls samples free of any other substance use to assess (...) the performance of a set of commonly used machine learning classifiers detecting AUD from resting state functional network connectivity derived from independent component analysis. The cohort used included 51 alcohol dependent subjects and 51 control subjects. Despite alcohol, none of the 102 subjects reported use of nicotine, cannabis or any other dependence or habit formation substance. Classification features consisted of whole brain rsFNC estimates undergoing a feature selection process using a random forest approach. Features were then fed to 10 different machine learning classifiers to be evaluated based on their classification performance. A neural network classifier showed the highest performance with an area under the curve of 0.79. Other good performers with similar AUC scores were logistic regression, nearest neighbor, and support vector machine classifiers. The worst results were obtained with Gaussian process and quadratic discriminant analysis. The feature selection outcome pointed to functional connections between visual, sensorimotor, executive control, reward, and salience networks as the most relevant for classification. We conclude that AUD can be identified using machine learning classifiers in the absence of nicotine comorbidity. (shrink)

En este texto analizaremos el decir filosófico zubiriano con el que pretende expresar la realidad de modo pleno y adecuado. En esto nos daremos cuenta de un grave y radical problema: la lengua que le ha sido dada social e históricamente al filósofo, la lengua en la que vive y se mueve intelectivamente y la lengua en la que quiere expresarse filosóficamente no coinciden en nada. La primera, la lengua vivencial, es una lengua románica y, por tanto, hunde sus raíces (...) en el indoeuropeo; en cambio, la segunda, la lengua filosófica, está incardinada desde la estructura lingüística semítica. ¿Por qué Zubiri busca acusar con tanto afán la realidad de un modo semítico y no lo hace en el indoeuropeo que habla y piensa? Aquí radica toda la cuestión fundamental que debemos analizar. A pesar de todas las dificultades que traerá para el desarrollo, claridad y divulgación del pensamiento zubiriano, se prefiere insistir rotundamente en el uso de la estructura semítica para expresar la realidad). Esta postura radical del pensador no es un mero capricho, sino una necesidad que se le impone (por lo menos, así lo piensa él). Y se le impone en y por la realidad misma que aprehende sentientemente. A raíz de esto, pensamos que Zubiri puede ser considerado como un pensador posmoderno". (shrink)

En esta investigación se busca analizar, a través de un texto fundamental de la obra Ciencia de la Lógica de Hegel, que versa sobre la línea nodal de relaciones de medida, un modo distinto tanto de hacer filosofía como de comprender la relación que se da entre la naturaleza y el espíritu.

No es posible seguir pensando a Zubiri desde su gran libro "Sobre la esencia" sin tener en cuenta la inmensa obra que levantó al final de su vida: "Inteligencia sentiente". Desde esta última obra, el filósofo español nos muestra la Noología y desde ella podemos ver no solamente las grandes posibilidades que nos ofrece el pensamiento último de Zubiri para resolver grandes problemas que las filosofías del siglo XX intentaron resolver, sino también para tomar distancia total de la Fenomenología de (...) Husserl y de las filosofías que nacieron de ella. Este artículo busca introducirse en esas cuestiones y señalar cómo la Fenomenología fue un espejismo necesario para el siglo pasado y cómo Zubiri desde ella y contra ella fue constituyendo su propia obra de madurez. (shrink)

Lo que se pretende con este artículo es pensar el Ereignis de Heidegger a la luz del problema del Sein en un triple referente; el cual se muestra en tres palabras fundamentales: Wink, Aufriss y Destruktion. Esto nos llevará a estudiar someramente a nuestro autor desde los cursos de los años veinte anteriores a Sein und Zeit hasta el Seminario de Le Thor de 1969. Pero todo este horizonte de pensamiento estará articulado desde los Beiträge zur Philosophie. Vom Ereignis (1936-38).

Attention is often conceived as a gateway to consciousness . Although endogenous spatial attention may be independent of conscious perception , exogenous spatial orienting seems instead to be an important modulator of CP . Here, we investigate the role of auditory alerting in CP in normal observers. We used a behavioral task in which phasic alerting tones were presented either at unpredictable or at predictable time intervals prior to the occurrence of a near-threshold visual target. We find, for the first (...) time in neurologically intact observers, that phasic alertness increases CP, both objectively and subjectively. This result is consistent with evidence showing that phasic alerting can ameliorate the spatial bias exhibited by visual neglect patients . The alerting network may increase the activity of fronto-parietal networks involved in top-down amplification required to bring a stimulus into consciousness. (shrink)

RESUMENEste artículo es un intento de pensar lo que es el cuerpo a la luz de las filosofías de Gilles Deleuze y de Xavier Zubiri. Ambos pensadores han sido muy radicales en sus posiciones respecto al papel del sentir. A veces es más conocido, para algunos, el pensamiento deleuziano en torno al cuerpo y las sensaciones, pero la reflexión zubiriana es también una filosofía del cuerpo que a veces no ha sido atendida en su profundidad. Además, vemos que ambos pensadores (...) tienen muchos puntos en común; uno de ellos es el denominado «Cuerpo sin órganos». Desde esta categoría deleuziana se indicará la proximidad con la filosofía zubiriana y con ello la importancia que cobra el cuerpo en una filosofía para los tiempos actuales.PALABRAS CLAVEDELEUZE, ZUBIRI, LÓGICA, IMPRESIÓN, SENSACIÓN, CUERPO SIN ÓRGANOS, INTELIGENCIA SENTIENTE.ABSTRACTThis article attempts to think what the body is from the perspective of the philosophy of Gilles Deleuze and also from Xavier Zubiri. Both thinkers have been totally radicals in their positions concerning the role of sensations. It may sound more natural, for some, to associate Deleuze’s thought on body and sensations than that of Zubiri; but we have to acknowledge that the latter’s thought is also a philosophy of the body and, therefore, we shall attend it in its whole depth. Moreover, we have to recognize that both thinkers have lots of common points, one of them the so-called «Body without organs». From this deleuzian category will be indicated the proximity between deleuzian and zubirian philosophy; and with that the importance that acquires the body in a philosophy worth of our times.KEY WORDSDELEUZE, ZUBIRI, LOGIC, IMPRESSION, SENSATION, BODY WITHOUT ORGANS, SENTIENT INTELLIGENCE. (shrink)

Husserl comenzó oponiéndose a la posibilidad de considerar el yo como centro de referencia esencial de los actos intencionales. Sin embargo, luego aceptó incluirlo en la descripción fenomenológica como centro de referencia de las vivencias intencionales. Se analizan esos dos momentos y se estudia su posible correlación con la teoría kantiana del yo, para hacer énfasis, finalmente, en una importante diferencia entre ambos autores.

The reinforcement sensitivity theory proposes that neurobiological systems mediate protective and appetitive behaviours and the functioning of these systems is associated to personality traits. In this manner, the RST is a link between neuroscience, behaviour, and personality. The theory evolved to the present revised version describing three systems: fight-flight-freezing, behavioural approach/activation, and behavioural inhibition. However, the most widely available measure of the theory, the BIS/BAS scales, only investigates two systems. Using a large longitudinal community survey, we found that the BIS/BAS (...) scales can be re-structured to investigate the three systems of the theory with a BIS scale, three BAS scales, and a separate fight-flight-freezing system scale. The re-structured scales were age, sex, and longitudinally invariant, and associations with personality and mental health measures followed theoretical expectations and previously published associations. The proposed framework can be used to investigate behavioural choices influencing physical and mental health and bridge historical with contemporary research. (shrink)

El presente artículo busca dar con la influencia de Baruch Spinoza en el pensamiento de Xavier Zubiri en torno al tema de la materia y de allí entender lo que es lo estético. Es sabido que Zubiri desde joven fue un gran lector de Spinoza; incluso lo enseñaba en detalle a su amiga-estudiante María Zambrano. Y lo que pensamos es que Zubiri siempre estuvo influenciado por el pensador holandés y esto se ve reflejado en cómo Zubiri trata su concepto de (...) materia, clave en su obra; y tal concepto nos permite, por ejemplo, entender lo estético en el pensador español. (shrink)

Indecent Theology has provided both Feminist Theology and Liberation Theology with new contours for rethinking bodies, power, dominance, and submission. With regard to the logic of dominance that radically pushes the margins of the margins into a form of inexistent living, I suggest a material turn to rethink the contours that are evoked with Indecent Theology. Materialism has long stood as a philosophy opposing the overwhelming dominance of language and the poststructuralist emphasis that has emerged as the ‘linguistic turn’. Considering (...) ‘new materialism’ as a theoretical platform to reread Indecent Theology provides theologies and ethics an opportunity to re-imagine indecent methodologies through indecency, a sort of ethical perversion. I suggest an indecent turn in mobilizing materialism and kink as theories to reread indecent theology for a productive queer materialist sexual theology. The feminist liberation theology of Marcella Althaus-Reid pushes both feminism and liberation into new contours of power and submission and initiates new contours of queer sexuality into the discourse. When analysing Althaus-Reid’s work, we are brought to attention to the margins of the margins, an awareness of the struggle for power and control by those deemed less than. There are contours of power at and in the margins of the margins, those who occupy ‘bottom space’. From a kink/bdsm orientation, I propose to reread Alrhaus-Read’s feminist liberation theology as decolonial erotics that helps to generate a productive materialist queer sexuality. The overarching methodology of this article is a quasi-auto ethnographic investigation into the ways in which the contours of race, class, gender, sex, sexuality, and ability affect power and submission and in turn reframes both queer theology and queer sexuality that is rooted in the living out of a very particular theology and ethics, which is rooted in queer relating. Theology can neither materialize in a vacuum nor in isolation. An indecent turn to a queer sexual theology that is rooted in a queer relationality demands attention to the interdependence of queer relating that is materialized through the interdependency of the growing queer desires of bodies, power, dominance, and submission. (shrink)

En este texto se analiza la importancia de la construcción o el fortalecimiento de la autoridad y confianza epistémicas desde la perspectiva de primera persona de las mujeres y cómo estas cualidades se pueden explorar en su íntima conexión con la confianza corporizada. Las mujeres, a través de sus experiencias particulares de sí mismas, del mundo y de los otros, asimilan de manera perjudicial la desconfianza epistémica que su comunidad de conocimiento les transmite. Se desarrolla esta tesis con base en (...) la concepción fenomenológica de cuerpo vivido, tal como fue planteada por Merleau-Ponty, pero con un énfasis en los trabajos de Simone de Beauvoir e Iris Young, pues son estos los que permiten comprender cómo las estructuras fundamentales de la experiencia y los modos de ser corporizados de las mujeres recorren una ruta experiencial diferente a la de los hombres en razón del tipo de sociedad en que se encuentran. En la parte final del texto se propone una manera de reconstruir o fortalecer la confianza y autoridad epistémicas de las mujeres a partir de una ruta de autoconocimiento corporizado y del cambio de hábitos. (shrink)

RESUMO O intuito deste artigo é estudar o objetivo principal da estética musical de Boulez, para o início das comemorações de seus 90 anos, desde certas categorias de Deleuze, considerando que elas nos permitem compreender e delinear uma lógica da sensação sonora. Se Deleuze se ocupou em detalhe do trabalho de Francis Bacon, por exemplo, a fim de criar uma "lógica da sensação visual" em que o conceito de "Figura" fosse central, propomos que o trabalho musical de Boulez, analisado a (...) partir do pensamento de Deleuze, possa mostrar os momentos decisivos de uma "lógica da sensação sonora." Por meio de alguns trabalhos de Boulez podemos ver dois elementos muito importantes para nossa pesquisa dados na estrutura instalada pela filosofia de Deleuze. Esses dois elementos que darão forma a este artigo são: as "figuras" da música e as "forças" do som expressivo. ABSTRACT This article aims to study the main objective of musical aesthetics of Boulez, to begin to commemorate 90 years, since certain categories of Deleuze, as they allow us to understand and outline a logic of sound sensation. If Deleuze worked in detail the work of Francis Bacon, for example, to create a "logic of visual sensation" where the concept of "Figure" is central, we propose that the musical work of Boulez, analyzed from Deleuze's thought, be possible to show the decisive moments of a "logic of sound sensation." Along some works by Boulez we can see two very important elements for our research in the framework installed Deleuze's philosophy are given. These two elements will shape this article are: the "figures" of music and the "forces" expressive sound. (shrink)

El presente texto en que Augusto A. Bolívar entrevista a Norbert Lechner, se profundiza sobre un conjunto de temas tales como los de “heterogeneidad estructural” y “hegemonía externa”, la distinción entre modernización y modernidad, “racionalidad normativa”, la tensión entre voluntad y necesidad y entre acción y condicionamiento, la autoproducción como comunidad de la sociedad moderna, las distinciones entre lo político con lo estatal y con lo público, lo que lleva a un análisis de la nueva ciudadanía, y finalmente se aborda (...) el desafío de los procesos de la modernidad y la modernización en el caso chileno, abordando sus tensiones junto a las propuestas para resolverlas. (shrink)

In this article, I present the structural consequences generated by the continuous and systematic epistemic injustices carried out in certain communities or institutions. These injustices contribute to building a structure of silencing, denial of epistemic authority, cover-up and impunity. The importance of the normative aspect that guides the reflections about these injustices will be exposed in two senses: on the one hand, insofar as it is necessary to have criteria that allow establishing the truth in the background of evaluation of (...) epistemic injustices and, on the other, in the sense of specifying how systematically attempting against it produces almost irreversible epistemic damage and guarantees the perpetuation of the structure. It will be shown how this happens within the framework of a powerful institution such as the Catholic Church, which has exhibited a pattern of testimonial injustices and the cover-up of abuses within it for decades. (shrink)

Introducción: Se presenta un análisis cualitativo del acompañamiento psicosocial a jóvenes en condiciones de vulnerabilidad desde la ecología humana durante 12 meses entre 2010 a 2011; utilizando técnicas pedagógicas evaluativas participativas. Éstas, son una alternativa para crear espacios reflexivos con el propósito de potenciar la resiliencia en las relaciones comunicativas y formar en el respeto. Objetivo: Generar bienestar, prevenir la farmacodependencia y contribuir a la promoción de la salud. Material y Métodos: Se revisaron los antecedentes temáticos, fueron seleccionados 100 estudiantes (...) entre 11 y 19 años de dos instituciones educativas públicas en condiciones vulnerables;se desarrollaron cuatro talleres reflexivos y cuatro prácticas lúdicas y se realizaron tres grupos focales con estudiantes, profesores y padres de familia. Resultados y Discusión: El contexto social de la población intervenida, revela problemas de abuso sexual, violencia intrafamiliar y eventos violentos en el vecindario por grupos armados ilegales, entre otros, que constituyen factores de riesgo importantes para la farmacodependencia. Conclusión: Se infiere que lo psicosocial incide en la farmacodependencia, afectando la convivencia de la población estudiada por múltiples causas del orden psicoafectivo, sociocultural, económico y político que van desde el consumo cultural hasta la seguridad alimentaria. Introduction: A qualitative analysis of the psycho-social support to young people in situations of vulnerability from human ecology is presented for 12 months between 2010 to 2011; using participatory evaluative pedagogical techniques. These are an alternative to create reflective spaces with the purpose of enhancing resilience in communicative relationships and working in respect. Objective: to generate well-being, prevent drug abuse and contribute to the health promotion. Material aids and methods: the thematic background was reviewed, 100 students between 11 and 19 years of two public schools in vulnerable conditionswere selected; four reflective workshops and four playful practices were developed and three focus groups with students, teachers and parentswere conducted. Results and discussion: the social context of the manipulated population reveals sexual abuse problems, domestic violence and violent events in the neighborhood by illegal armed groups, among others, which constitutemajor risk factors for drug abuse. Conclusion: It can be inferred that the psychosocial factors impact on drug dependence, affecting the coexistence of the population studied by multiple causes of the psychological, socio-cultural, economic and political order, ranging from cultural consumption to food security. (shrink)

El objetivo del estudio fue sistematizar y analizar el pensamiento filosófico de Bruno sobre la concepción de magia en el renacimiento. La importancia de la investigación fue entender la cosmovisión bruneana que sigue vigente en el desarrollo del avance de la ciencia. Siendo la conclusión que el concepto de mago es equivalente a sabio, y se manifiesta a través de los tipos de magia: Divina, Física, Matemática y en función del vínculo entre el mago y la naturaleza: magia natural, fantasmagórica, (...) magia natural por virtud, magia matemática, de los desamparados, nigromancia, maléfico, adivinación y profecía. (shrink)

This research delved into the analysis of the role of institutional entrepreneurship within the Colombian business context, focusing on the process of divergent change promoted by entrepreneurs. Following the theory of institutional entrepreneurship, it examined how entrepreneurs operating in non-privileged positions within highly regulated industries challenge established conventions by developing new ventures. The study was underpinned by qualitative research of a descriptive nature, implementing a design based on a review of existing literature. The results of this analysis revealed that the (...) integration of traditional entrepreneurial skills with supplementary and complementary competencies, oriented towards new institutional logics, can constitute an effective strategy for entrepreneurial development in Colombia. Consequently, it is concluded that institutional entrepreneurship exerts a significant influence on entrepreneurial change within Colombia. This finding provides valuable insights for future research and for the design of policies to promote innovation and entrepreneurial development in the country. (shrink)

It is well known the harmful effects that savage capitalism has been causing to the environment since its introduction in a sphere in which a different logic and approach to nature are the essential conditions for the maintenance of the ecosystem and its complex relations between humans and non-human organisms. The amazon rainforest is a portion of the planet in which for thousands of years its human dwellers have been interacting with nature that it is understood beyond its physical condition. (...) Thus, to what extent Amazonian’s approaches to nature could be considered as a moral philosophy through which the way of conceptualizing nature and its non-human denizens enhances the continuity of life and the intimate relations between entities? To answer this question, I will explore the cosmological system of the Shuar of the Ecuadorian Amazon with whom I lived for 5 months between July and November 2018, and thereby elucidate the spiritual relations that this society has with the metaphysical domain of nature. (shrink)

Se indaga el problema de la explotación técnica del mundo a partir de los pensamientos de Xavier Zubiri y Georges Canguilhem. Se examina el análisis zubiriano de la inteligencia humana y la tesis de Canguilhem sobre la originalidad de la actividad técnica, su relación con la ciencia y su papel en la normatividad del organismo. En ambos autores, el término Umwelt, traducido como “circun-mundo” o medio de comportamiento propio, sirve como base para establecer las posibilidades que tiene la técnica en (...) el desarrollo de nuevas formas de relación con el medio ambiente. (shrink)

We introduce a novel experimental paradigm for eliciting metaphoric expressions in spontaneous speech, under controlled conditions. Participants were presented with a pair of words on a PC monitor and were asked to provide a verbal response describing a conceptual relation between the stimuli. The proportion of metaphoric responses depended on the stimuli in a predictable manner. A large proportion of metaphoric responses was obtained for stimuli that were derived from existing metaphors. The chronometric study of metaphor production in this paradigm (...) produced 3 major findings: (a) a figurative-literal difference: responses that included metaphorical expressions showed greater reaction times (RTs) than responses with only literal expressions; (b) familiarity effect: responses that included more-familiar metaphorical expressions showed smaller RTs than responses that included less-familiar metaphorical expressions; (c) degree of metaphoricity effect: responses that included highly metaphorical expressions showed greater RTs than responses that included less metaphorical expressions. We discuss the processing implications of these results. (shrink)

Emotional self-regulation in childhood and adolescence constitutes a growing interest in the scientific community, highlighting in recent years the need to observe its development in their daily life. Therefore, the objective of this systematic review is to characterize publications referring to the development of emotional self-regulation of people under 18 years-old, in natural contexts. Based on the PRISMA guidelines, searches are carried out in the Web of Science, Scopus and PsycINFO databases, and in Google Scholar until May 2020. After reviewing (...) the full text of 376 publications, 14 works are selected that are observed in their extrinsic, substantive and methodological characteristics based on the GREOM and MQCOM guidelines, by two independent evaluators. Most of the studies correspond to the last 20 years, increasing the interest in observing older children, in interaction with adults and/or in different cultures. They apply mixed methodologies, not always ascribing to a low intensity design. Strengths are observed regarding the collection and analysis of the quality of the data; and weaknesses related to the failure to record the duration and sequence of behaviors, highlighting the use of guidelines as guides for future research. (shrink)

En este artículo se analiza una recreación quijotesca en la novela de Graham Greene Monseñor Quijote. Para ello se utilizan dos términos procedentes del Derecho romano: los conceptos de autoridad y poder. En esta obra de Greene, la autoridad surge de los libros o de autores de libros, cuya lectura permite que la vida siga teniendo sentido. En Greene encontramos la estrategia de lectura conocida como las sortes virgilianae que permite a los personajes orientarse en las dificultades diarias. Sin embargo, (...) el poder está caracterizado por su condición iletrada, la ausencia de libros y su ignorancia. In this article a novel by Graham Greene entitled Monsignor Quixote is analysed, a book that involves a recreation of the novel by Cervantes. The author of this article employs two concepts from Roman law: authority and power in his analysis. In this work by Greene, authority arises from the books or the book writers, whose reading allows life to keep making sense. In Greene, a strategy of reading known as the sortes virgilianae is found and this allows the characters to get their bearings in the daily difficulties. However, power is described as illiterate, the absence of books and ignorance. (shrink)

RESUMEN Con un enfoque cualitativo y alcance descriptivo, el presente artículo tiene como objetivo sintetizar aspectos de materiales publicados en diversas fuentes relacionados con el estrés para lo cual se emplea el método de revisión bibliográfica. Durante el estudio se encontraron aspectos teóricos que permiten entender la evolución del concepto, acceder a modelos, evaluar la repercusión del fenónemo y constatar instrumentos para su evaluación, así como obtener sugerencias para controlarlo. Se concluye que el estrés puede ser percibido como positivo o (...) negativo según el manejo que hace cada individuo y su estilo de afrontarlo, es una manifestación relacionada con el proceso salud enfermedad en el que, para algunos, contribuye al crecimiento personal y en otros, a su malestar o enfermedad. ABSTRACT With a qualitative approach and descriptive scope, the present article takes as an objective to synthesize aspects of materials published in diverse sources related to the stress for which uses the method of bibliographical review. During the study there were theoretical aspects that allow understanding the evolution of the concept, gaining access to models, evaluating the aftereffect of the phenomenon and state instruments for their evaluation, as well as obtaining suggestions to control it. It was concluded that the stress can be perceived as positive or negative according to the handling that there does every individual and its style of confronting it, a declaration related to the process is a health illness in the one that, for some, contributes to the personal growth and in others, to its discomfort or illness. (shrink)

Hermafroditas, intersexos, andróginos, transexuales u homosexuales simbolizan el lugar de la fisura, de la frontera, de la disidencia en relación a los cuerpos sexuados, los géneros y las sexualidades. Constituyen a su vez un espacio discursivo privilegiado desde donde recorrer algunas de las certezas que se han ido produciendo y reproduciendo desde los distintos campos de conocimiento y poder a lo largo de la historia de Occidente. El análisis de categorías médico-sociales como el “hermafroditismo”, la “intersexualidad”, o la más recientemente (...) conocida como “DSD/ADS”, nos descubre un panorama complejo y a la vez controvertido, pero con el potencial suficiente para indagar en el carácter performativo de las categorías sociales. Además, nos permite adentrarnos en un debate bioético más amplio sobre los límites de las prácticas médicas, las cuestiones relativas al control y la normalización de cuerpos, o sobre la incorporación de nuevas tecnologías en la conformación de cuerpos e identidades. (shrink)

Throughout our entire evolutionary history, the physical environment has played a significant role in shaping humans’ subsistence adaptations. As early humans began to colonise novel biomes and construct ecological niches, their behavioural flexibility appeared as an unquestionable fact. During the Late Pleistocene-Holocene transition, the shift from foraging to farming radically altered ecosystem services, resulting in increased exposure to zoonotic pathogens and the emergence of structural inequalities that pervade our current human condition in the Anthropocene epoch. The article seeks to use (...) an anthropological biosocial analysis to explore the diverse evolutionary paths humans have taken, which in turn shape their relationships with the natural world. Given the enigmatic nature of human behavior, it is essential to examine it holistically to understand how different subsistence patterns (e.g., intensive agriculture, foraging, and horticulture) have influenced resilience and adaptation to environmental challenges. (shrink)

La tesis principal de este ensayo estipula que el determinismo causal es una propiedad de la naturaleza y el primer principio de la inteligibilidad natural. Se expresa, por ejemplo, en la frase de Lucrecio: “Nada surge de la nada ni va hacia la nada”. Todo lo que existe es efecto de una red de causas y es a su vez causa de otras cosas. Se sigue que la teoría científica orientada hacia la inteligibilidad —diferente de la ciencia positi-vista y pragmática— (...) es la búsqueda de determinismo causal. El desarrollo de esta tesis utiliza como hilo conductor el pensamiento de René Thom. Esto significa que el determinismo causal se examina en su rela-ción con (I) la estabilidad y la inestabilidad, (II) el desafío de la mecánica cuántica, (III) las raíces aporéticas de la ciencia tal como la dualidad determinismo-indeterminismo, y finalmente (IV) en su relación con el método para ponerlo de manifiesto, es decir la reducción de lo posible —estrategia que es, en este dominio, una de las ideas más originales de Thom.The main thesis of this essay is that causal determinism is a property of nature and the main principle of natural intelligibility. It can be expressed in Lucretius’ words: “Nothing comes out of nothing or passes into nothing”. Everything is the effect of a web of causes and is, in its turn, cause of something else. It follows that the essence of an intelligibility-oriented scientific theory —which is different from science in a positivist or pragmatist sense— is the search for causal determinism. The development of this thesis is guided by René Thom’s thought. This means that causal determinism is analysed, first, in its relation to stability and instability; second, in its relation to the prima facie indeterminism of quantum mechanics; third, in its relation to the aporetic roots of science such as the duality determinism —indeterminism, and, finally, in its relation to the method which allows science to follow the causal determinist ideal: the reduction of the possible— a strategy which is, in this field, one of Thom’s most original ideas. (shrink)